Welcome to Structural Skin Tightening

The next step in the evolution of skincare is here. It’s Structural Skin Tightening—A treatment that delivers all the skin tightening, collagen-boosting power of radiofrequency, with no numbing, needles, or downtime. Just visible results, backed by science and designed for comfort.
Unlike conventional RF treatments, the XERF™ treatment delivers energy deeper into the skin—reaching the shallow, middle, and deep layers—where real change begins.

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Results without sacrifice

  • No numbing, no needles, and no downtime.
  • True skin transformation at every level, delivering energy exactly where you need it most.
  • Fully customizable treatments that adapt to each patient’s unique skin profile.

How XERF Structural Skin Tightening works

The XERF system offers the world’s first multi frequency monopolar RF treatment. By combining both 6.78 MHz and 2 MHz frequencies, XERF can deliver energy not just deeper, but exactly where you need it most, creating smoother and tighter skin.

A treatment as unique as you are

No two individuals are alike, and their skin treatments shouldn’t be either. The XERF system adapts to each patient’s unique skin profile using Accurate Impedance Feedback for real-time analysis of the skin. With three depth settings and ten intensity levels, a XERF treatment is a truly personalized experience tailored for each individual patient.

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Before and after 2 treatments. Courtesy of Dianne Quibell, MD

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Before and after 4 weeks, Courtesy of Jordan Wang, MD

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Before and after 2 treatments. Courtesy of Dianne Quibell, MD

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The world’s first multifrequency monopolar RF treatment, The XERF Structural Skin Tightening treatment delivers energy into each patient’s skin exactly where they need it most. No needles, no numbing, and no downtime – just smoother and tighter skin, personalized for each patient.

Clinical Evidence

Monopolar radiofrequency for dermal temperature regulation and remodeling: A porcine model study

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Efficacy of dual-frequency noninvasive monopolar radiofrequency in skin tightening

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FAQ

What internal temperatures are created by the XERF system, and how were they measured?

In in-vivo studies, Cynosure Lutronic measured internal skin temperatures of 50°C, 60°C, and 70°C using ultrasound-guided fiber-optic imaging. Following the XERF treatment, histological analysis confirmed collagen remodeling.

How do you know XERF treatments strengthen collagen and tighten the skin?

Histological evidence from in-vivo porcine studies shows increased thickening and tightening of collagen bundles at multiple tissue depths, along with an observable upward pull in the fascia.

How do you know how deeply the XERF system delivers RF energy?

Histological analysis from multiple clinical studies confirms the XERF system delivers RF energy to the SMAS (Superficial Musculoaponeurotic System). The SMAS is a foundational tissue layer beneath the skin that plays a key role in lifting and tightening sagging skin and reducing the appearance of jowls.

Intended for distribution in Canada only.

The XERF™ system is intended as a non-invasive dermatological aesthetic treatment device with indications for facial lines and wrinkles, lift the eyebrow, and facial and neck laxity. Cynosure Lutronic does not diagnose or treat medical conditions, prescribe treatment protocols, provide medical advice, or otherwise practice medicine. Patient should consult with a qualified healthcare professional for diagnosis and proper treatment protocols/parameters to determine if treatment with any product is right for them. Qualified healthcare professionals are responsible for diagnosis and treatment protocols, and post treatment care using products.

©2025 CYNOSURE LUTRONIC, INC. All Rights Reserved. XERF and Lutronic are registered trademarks of Lutronic Corporation. Cynosure is a registered trademark of Cynosure, LLC.

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